We’ll know the 49ers’ entire schedule by 5 p.m. on Wednesday, but their opponents for Weeks 1 and 2 have already trickled out.
San Francisco will open the season in Detroit for an early 10 a.m. kickoff on Sept. 12 against the Lions, the team announced on Wednesday morning. Here’s an interesting fact: The last two times the 49ers have opened their season vs. the Lions — in 1981 and 1984 — they went on to win the Super Bowl.
The Week 1 will be an interesting one, featuring old friend Jared Goff in his first start as Lions quarterback, with new coach Dan Campbell at the helm.
The 49ers will stay on the road in Week 2, and head to Philadelphia for a matchup with the Eagles on Sept. 19, another 10 a.m. start, according to the Philadelphia Inquirer. It stands to reason that the 49ers will stay over on the East Coast during the week, something they have done in previous years under Shanahan.
Though we won’t know the specifics for a few hours, here are the other teams the 49ers will play in 2021:
Green Bay, Minnesota, Atlanta, Indianapolis, Houston and NFC West (Arizona, Seattle, Los Angeles Rams).
Chicago, Jacksonville, Tennessee, Cincinnati and NFC West (Arizona, Seattle, Los Angeles Rams).