(Photo by Lachlan Cunningham/Getty Images)

Sound the alarms?

Quietly appearing on the 49ers’ injury report Wednesday was George Kittle, who did not practice and reportedly is dealing with ankle soreness.

As inconceivable as a Kittle absence would be, his not practicing four days before the NFC Championship showdown with the Packers is significant.

Kittle missed two games earlier this season with knee and ankle issues but bounced back and finished the year strong.

The tight end is the best in football, finishing the year with 85 catches for 1,053 yards and five touchdowns. In the lone San Francisco-Green Bay matchup this season, the first-team All Pro caught six passes for 129 yards and a TD.